Plain Language Summary
Thalassaemia is a group of genetic blood disorders. Blood transfusion is needed for serious forms of the condition treated, but it leads to a high level of iron in the body. The excess iron is usually removed by drugs through 'chelation therapy'. Other less conventional treatment is bone marrow transplantation, which is restricted by age, and hydroxyurea, a drug designed to raise the level of fetal hemoglobin in collecting and anemia reduction . Psychological support would seem appropriate that thalassemia is a chronic disease with a major role for the control of a self-management. We were unable to find any trials to include in this review. There is a some reports that people learn about their condition improve compliance with chelation therapy. But from the information currently available, we can not recommend the use of specific psychological therapy in thalassemia. We believe there is a need for a big test the value of psychological therapy for thalassemia evaluate.
Abstract
Background: Thalassaemia is a group of genetic blood disorders characterized by the absence or reduction in the production of hemoglobin. Severity is variable from less severe anemia by thalassemia intermedia, deeply serious anemia (thalassemia major). In thalassemia major other complications that delayed growth, bone deformation, and an enlarged spleen. Blood transfusion is needed for severe forms of thalassemia treatment, but this results in excessive accumulation of iron in the body (iron overload), removed mostly by a drug called Desferrioxamine by chelation therapy. Non-routine treatment is bone marrow transplantation (that age limit), and possibly hydroxyurea, designed to raise the level of fetal hemoglobin to raise, and thus anemia. In addition, psychological therapy seems appropriate for improving the outcome and adherence to medical treatment.
Objectives: proof that people with thalassemia, psychological treatments improve the ability to handle the situation, and the improvement of both the medical and psychosocial outcomes research.
Search methods: We went to the Cochrane cystic fibrosis and genetic disorders haemoglobinopathies Group Trials Register comprising references from comprehensive electronic database searches and handsearches of relevant journals and abstract books of conference proceedings. Search the Internet are also exported.
Date of most recent search of the Group's Trials Register haemoglobinopathies: October 27, 2011.
Selection criteria: All randomized or quasi-randomized controlled trials comparing the use of psychological intervention (psychological) intervention in people with thalassemia.
Data collection and analysis: No trials of psychological therapy were found in the literature for inclusion in this review.
Main results: There are currently no results reported.
Authors' conclusions: As a chronic disease with a major role for the control of a self-psychological support seems appropriate for the management of thalassemia. But from the information currently available, no conclusions about the use of specific psychological therapy in thalassemia. This systematic review has clearly identified the need for well designed, adequately powered, multicenter, randomized controlled trials to assess the efficacy of specific psychological interventions for thalassemia.
Background: Thalassaemia is a group of genetic blood disorders characterized by the absence or reduction in the production of hemoglobin. Severity is variable from less severe anemia by thalassemia intermedia, deeply serious anemia (thalassemia major). In thalassemia major other complications that delayed growth, bone deformation, and an enlarged spleen. Blood transfusion is needed for severe forms of thalassemia treatment, but this results in excessive accumulation of iron in the body (iron overload), removed mostly by a drug called Desferrioxamine by chelation therapy. Non-routine treatment is bone marrow transplantation (that age limit), and possibly hydroxyurea, designed to raise the level of fetal hemoglobin to raise, and thus anemia. In addition, psychological therapy seems appropriate for improving the outcome and adherence to medical treatment.
Objectives: proof that people with thalassemia, psychological treatments improve the ability to handle the situation, and the improvement of both the medical and psychosocial outcomes research.
Search methods: We went to the Cochrane cystic fibrosis and genetic disorders haemoglobinopathies Group Trials Register comprising references from comprehensive electronic database searches and handsearches of relevant journals and abstract books of conference proceedings. Search the Internet are also exported.
Date of most recent search of the Group's Trials Register haemoglobinopathies: October 27, 2011.
Selection criteria: All randomized or quasi-randomized controlled trials comparing the use of psychological intervention (psychological) intervention in people with thalassemia.
Data collection and analysis: No trials of psychological therapy were found in the literature for inclusion in this review.
Main results: There are currently no results reported.
Authors' conclusions: As a chronic disease with a major role for the control of a self-psychological support seems appropriate for the management of thalassemia. But from the information currently available, no conclusions about the use of specific psychological therapy in thalassemia. This systematic review has clearly identified the need for well designed, adequately powered, multicenter, randomized controlled trials to assess the efficacy of specific psychological interventions for thalassemia.